Program Highlight: Plenary Session 4 – Cell Therapy and Tissue Engineering II
|Chair: Amit Patel, MD, MS, University of Utah, United States|
Update in Cardiac Biological Therapies
Amit Patel, MD, MS, University of Utah, United States
- Understand the issues with first generation biologics
- Identify positive studies for cardiovascular biologics
- Identify patients for clinical trials
Injectable extracellular matrix hydrogels for regenerative medicine
Karen Christman, PhD, FAHA, University of California San Diego, United States
- Learn about the state of the art in injectable biomaterials for treating myocardial infarction and peripheral artery disease
- Learn about injectable decellularized extracellular matrix materials
- Learn about cell delivery using injectable biomaterials
Preclinical Testing of Cell Therapy for Skeletal Muscle Dysfunction
Tracy Criswell, PhD, Wake Forest Institute for Regenerative Medicine, United States
- Preclinical small animal models of skeletal muscle dysfunction, useful for testing cell therapy will be discussed, with a concentration on a model of acute muscle injury used predominantly by our group.
- The types of cells used for therapy will be discussed, including allogeneic muscle progenitor cells and a xenogeneic model using human muscle progenitor cells.
- Biological and pharmacological factors that can be used in conjunction with cell therapy will be discussed with a primary concentration on growth factors that can be used to modify the local microenvironment of the damaged tissue in order to increase transplanted cell survival and integration.